In addition to the conventional complexes, as enzyme-inhibitor and antibody-antigen, interactions can also be established between domain-domain and domain-peptide. A protein complex assembly can result in the formation of homo-oligomeric or hetero-oligomeric complexes. To describe the types of protein–protein interactions (PPIs) it is important to consider that proteins can interact in a 'transient' way (to produce some specific effect in a short time) or to interact with other proteins in a 'stable' way to build multiprotein complexes that are molecular machines within the living systems.
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